Schwann cells promote sensory neuron excitability during development
Husniye Kantarci, Pablo D. Elvira, Arun P. Thottumkara, Manasi Iyer, Lauren J. Donovan, Micaela Q. Dugan, Nicholas Ambiel, Emma M. O’Connell, Alejandro A. Granados, Hong Zeng, Nay Lui Saw, Amanda Brosius Lutz, Steven A. Sloan, Erin E. Gray, Khanh V. Tran, , J. Bradley Zuchero
This study shows Schwann cells promote sensory neuron excitability during development by secreting prostaglandin E2, which is essential for normal sodium channel expression and action potential firing.
bioRxiv · Oct 31, 2022 · PreprintNeuroscience