Author

Lauren J. Donovan

Stanford MedicineORCID 0000-0002-5622-7402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Vivianne L. TawfikiD· 3 shared Claire E. JordaniD· 2 shared Sabrina F. BondiD· 2 shared Aditi AgrawaliD· 1 shared Aditi Vichare· 1 shared Akshay PujariiD· 1 shared Aleishai Pena Lopez· 1 shared Alejandro A. GranadosiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Vivianne L. TawfikORCID

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Author profile →

3 papers

Recent·Most cited

Aging and injury drive neuronal senescence in the dorsal root ganglia

Lauren J. Donovan, Chelsie L. Brewer, Sabrina F. Bond, Alexander M Laslavic, Aleishai Pena Lopez, Laura Colman, Claire E. Jordan, Linus Hansen, Oscar Christian Gonzalez, Akshay Pujari, Luı́s de Lecea, Marco Quarta, Julie A. Kauer, Vivianne L. Tawfik

This study identifies neuronal senescence in dorsal root ganglia of aged and injured mice, showing it contributes to sensory dysfunction and is reversible with senolytic treatment.

Nature Neuroscience · May 1, 2025Peer-reviewedNeuroscience

Newly repopulated spinal cord microglia exhibit a unique transcriptome and correlate with pain resolution

Lauren J. Donovan, Caldwell M. Bridges, Amy R. Nippert, Meng Wang, Shaogen Wu, Thomas E. Forman, Elena S. Haight, Nolan A. Huck, Sabrina F. Bond, Claire E. Jordan, Aysha S. Gardner, Ramesh V. Nair, Vivianne L. Tawfik

The paper shows that newly repopulated spinal cord microglia have a unique transcriptome linked to pain resolution in a tibial fracture model.

bioRxiv · Dec 20, 2022 · PreprintNeuroscience

Schwann cells promote sensory neuron excitability during development

Husniye Kantarci, Pablo D. Elvira, Arun P. Thottumkara, Manasi Iyer, Lauren J. Donovan, Micaela Q. Dugan, Nicholas Ambiel, Emma M. O’Connell, Alejandro A. Granados, Hong Zeng, Nay Lui Saw, Amanda Brosius Lutz, Steven A. Sloan, Erin E. Gray, Khanh V. Tran, , J. Bradley Zuchero

This study shows Schwann cells promote sensory neuron excitability during development by secreting prostaglandin E2, which is essential for normal sodium channel expression and action potential firing.

bioRxiv · Oct 31, 2022 · PreprintNeuroscience