HSF1 controls transcriptional programs that establish thalamostriatal shaft synaptic architecture and preserve cognitive flexibility
Nicholas B Rozema, Nicole Zarate, Rachel H. Mansky, Persephone Gu, Kinsey Gerlach, Aishwarya Bhowmik, James H. Cho, Ying Zhang, Arif Hamid, Steven M. Graves, Rocío Gómez‐Pastor
This study identifies HSF1's role in regulating thalamostriatal synapses and cognitive flexibility by controlling transcriptional programs and actin dynamics.
bioRxiv · Aug 7, 2026 · PreprintNeuroscience