Nicole Zarate

This study identifies HSF1's role in regulating thalamostriatal synapses and cognitive flexibility by controlling transcriptional programs and actin dynamics.

This study shows that reducing CK2 in HD mice improves neuroinflammation, HTT aggregation, and motor deficits by reducing synucleinopathy.

The paper examines changes in astrocyte subtypes in HD mouse models, finding increased GFAP+ astrocyte density and clustering in specific striatal regions.

This study links in vivo 1H-MRS neurochemical changes to specific synaptic pathway alterations in a Huntington's disease mouse model.

The paper shows that egl-1, a BH3-only gene in C. elegans, is transcriptionally regulated by neuronal activity and kinases in adult sensory neurons without inducing apoptosis.