Author

Faith Conroy

University of Massachusetts Chan Medical SchoolORCID 0000-0002-9934-7308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia KhvorovaiD· 2 shared Dimas EcheverriaiD· 2 shared Julia F. AltermaniD· 2 shared Neil Aronin M. DiD· 2 shared Adel BoudiiD· 1 shared Aikaterini Smaragdi PapadopoulouiD· 1 shared Arzo Iqbal· 1 shared Bruno M.D.C. GodinhoiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Anastasia KhvorovaORCID

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2 papers

Recent·Most cited

Lowering the HTT1a transcript as an effective therapy for Huntingtons disease

Aikaterini Smaragdi Papadopoulou, Julia F. Alterman, Christian Landles, Edward J. Smith, Faith Conroy, Jemima M Phillips, María Cañibano-Pico, Iulia M Nita, Georgina F Osborne, Arzo Iqbal, Sarah G. Aldous, Marie K. Bondulich, Casandra Gomez-Paredes, Kirupa Sathasivam, Daniel O’Reilly, , Gillian P. Bates

The paper shows that lowering HTT1a transcript levels delays molecular and neuropathological phenotypes in a Huntington's disease mouse model.

bioRxiv · Jun 10, 2025 · PreprintNeuroscience

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in vivo in CNS

Faith Conroy, Rachael Miller, Julia F. Alterman, Matthew R. Hassler, Dimas Echeverria, Bruno M.D.C. Godinho, Emily G. Knox, Ellen Sapp, Jaquelyn Sousa, Ken Yamada, Farah Mahmood, Adel Boudi, Kimberly B. Kegel-Gleason, Marian DiFiglia, Neil Aronin M. D, , Edith L. Pfister

This paper demonstrates allele-specific siRNA silencing of mutant huntingtin in CNS using SNP-based targeting in vitro and in vivo.

bioRxiv · Jun 29, 2022 · PreprintNeuroscience