Author

Krishna Jayasankar

Indiana University School of Medicine

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Avinash SoundararajaniD· 1 shared Emma H. DoudiD· 1 shared Michelle L. SurmaiD· 1 shared Padmanabhan Paranji PattabiramaniD· 1 shared Rodahina Philihina Pasteurin· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Avinash SoundararajanORCID

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1 paper

Recent·Most cited

Loss of Cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork

Avinash Soundararajan, Krishna Jayasankar, Emma H. Doud, Rodahina Philihina Pasteurin, Michelle L. Surma, Padmanabhan Paranji Pattabiraman

This study shows that loss of Cathepsin K disrupts collagen biogenesis, ECM homeostasis, and actin polymerization in trabecular meshwork cells, potentially affecting aqueous humor outflow and IOP regulation.

Investigative Ophthalmology & Visual Science · Jan 30, 2026Peer-reviewedCell Biology