Author

Krista Grimes

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Gabriel AugheyiD· 2 shared Tony D. SouthalliD· 2 shared Alicia Estacio‐GómeziD· 1 shared Carmen Bravo González‐BlasiD· 1 shared Dafni PapasokratiiD· 1 shared Elhana Forsberg· 1 shared Florian V. De RopiD· 1 shared Gert J. HulselmansiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersDevelopmental Biology

Gabriel AugheyORCID

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2 papers

Recent·Most cited

NuRD independent Mi-2 activity represses ectopic gene expression during neuronal maturation.

Gabriel Aughey, Elhana Forsberg, Krista Grimes, Shen Zhang, Tony D. Southall

The paper shows Mi-2 activity represses ectopic gene expression in neurons independently of NuRD, highlighting its role in establishing stable neuronal transcriptomes during early differentiation.

EMBO Reports · Feb 1, 2023Peer-reviewedDevelopmental Biology

Decoding gene regulation in the fly brain

Jasper Janssens, Sara Aibar, Ibrahim Ihsan Taskiran, Joy N. Ismail, Alicia Estacio‐Gómez, Gabriel Aughey, Katina I. Spanier, Florian V. De Rop, Carmen Bravo González‐Blas, Marc Dionne, Krista Grimes, Xiao‐Jiang Quan, Dafni Papasokrati, Gert J. Hulselmans, Samira Makhzami, , Stein Aerts

The paper identifies regulatory regions and gene regulatory networks in Drosophila brain cell types using chromatin accessibility and transcriptome data.

Nature · Jan 5, 2022Peer-reviewedGenomics