Gabriel Aughey

The paper identifies biallelic variants in ARHGAP19 as a cause of motor-predominant neuropathy with conduction slowing in multiple families.

This study shows that gain-of-function BK channel mutations disrupt limb control in fruit flies by altering neuronal development during a critical period, not by affecting mature circuits.

The paper shows Mi-2 activity represses ectopic gene expression in neurons independently of NuRD, highlighting its role in establishing stable neuronal transcriptomes during early differentiation.

The paper identifies how Shavenbaby isoforms regulate gene expression and chromatin structure during Drosophila intestinal stem cell differentiation.

AGES provides a non-lethal, cost-effective method to temporally control GAL4 activity in Drosophila by using auxin to degrade GAL80, enabling precise gene expression regulation.

The paper identifies regulatory regions and gene regulatory networks in Drosophila brain cell types using chromatin accessibility and transcriptome data.

This study identifies a novel crosstalk between Drosophila intestinal stem cells and the tracheal system, showing that reactive oxygen species drive tracheal plasticity to support intestinal regeneration.

The paper introduces FlyORF-TaDa, a system that rapidly generates transgenic Drosophila lines for cell-type specific profiling of protein-DNA interactions using existing FlyORF libraries.

This study shows that Cap-G, a condensin I subunit, is essential for proper gene expression in post-mitotic neurons, leading to developmental arrest and gene expression changes when knocked down.

The paper uses an in vivo method to profile chromatin accessibility in Drosophila stem cell lineages, revealing dynamic changes during differentiation.