Author

Kristen M. Bartoli

Massachusetts Institute of Technology

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Molecular Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Organism:yeast· 1

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Cassandra Schaening-BurgosiD· 1 shared Thomas M. CarlileiD· 1 shared Wendy V. GilbertiD· 1 shared

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2018-2018 · peak 1/yr

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Cassandra Schaening-BurgosORCID

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Recent·Most cited

Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl Ribose

Kristen M. Bartoli, Cassandra Schaening-Burgos, Thomas M. Carlile, Wendy V. Gilbert

The paper identifies 2′-O-methyl ribose (Nm) as a prevalent mRNA modification in yeast, showing that Spb1 methylates ribosomal protein mRNAs and that its expression is required for normal levels of target mRNAs.

bioRxiv · Mar 8, 2018 · PreprintMolecular Biology