MST1R/RON and EGFR in a complex with syndecans sustain carcinoma S-phase progression by preventing p38MAPK activation
DeannaLee M. Beauvais, Kristin Short, Noah Stueven, Scott E. Nelson, Denis Lee, Oisun Jung, Richard A. Anderson, Paul F. Lambert, Alan C. Rapraeger
The paper shows that MST1R/RON and EGFR form a complex with syndecans that prevents p38MAPK activation, sustaining S-phase progression in carcinoma cells by inhibiting DNA replication stress.
bioRxiv · Jan 24, 2018 · PreprintCancer Biology