Author

Kristján Hermannsson

University of Iceland

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

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Andrea García‐LlorcaiD· 1 shared Eirı́kur Steingrı́mssoniD· 1 shared Filippo LocriiD· 1 shared Helder AndréiD· 1 shared Margret Helga OgmundsdottiriD· 1 shared Þór EysteinssoniD· 1 shared

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Andrea García‐LlorcaORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMay 25, 2026

MITF is essential for autophagy in the retinal pigment epithelium

Andrea García‐Llorca, Kristján Hermannsson, Filippo Locri…·Þór Eysteinsson

This study shows that MITF regulates autophagy in RPE cells, with reduced MITF causing autophagy defects and lysosomal dysfunction linked to retinal degeneration.

DOI 10.64898/2026.05.22.727222

mousehuman

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