Margret Helga Ogmundsdottir

This study identifies ATG7(2) as a driver of pancreatic cancer progression independent of autophagy, showing its role in promoting proliferation, migration, and tumor growth.

This study shows that MITF regulates autophagy in RPE cells, with reduced MITF causing autophagy defects and lysosomal dysfunction linked to retinal degeneration.

The paper identifies ATG7 as a genetic risk factor for cholangiocarcinoma through germline mutations and population studies, linking autophagy dysfunction to cancer development.