Proteolytic control of mitochondrial calcium transport by intermembrane-space proteases
Anupriya Sinha, Kunal Samantaray, Ashlesha A. Kadam, Pooja Jadiya, Dhanendra Tomar
This study identifies IMS proteases as regulators of mitochondrial calcium transport by remodeling mtCU and NCLX through proteolytic control, linking proteostasis to Ca2+ homeostasis.
bioRxiv · Aug 22, 2026 · PreprintCell Biology