Pooja Jadiya

This study identifies IMS proteases as regulators of mitochondrial calcium transport by remodeling mtCU and NCLX through proteolytic control, linking proteostasis to Ca2+ homeostasis.

This study shows that reducing neuronal mitochondrial calcium uptake in AD mouse models decreases pathology, synaptic dysfunction, and cognitive decline.

This study identifies mitochondrial lactylation changes in myocardial infarction and shows that MCT1 inhibition alters lactylation, reduces fibrosis, and partially restores mitochondrial function.

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

This study investigates age-related changes in mitochondrial structure and function in the liver, identifying MICOS complex dysregulation as a contributor to metabolic and structural impairments.