Author

Kyle Chen

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Arie KaffmaniD· 1 shared Basavaraju G. SanganahalliiD· 1 shared Christian Bowers· 1 shared Fahmeed HyderiD· 1 shared Jose Munoz-MartiniD· 1 shared Lauryn GiulianoiD· 1 shared Sahabuddin AhmediD· 1 shared Sumit JamwaliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Arie KaffmanORCID

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1 paper

Recent·Most cited

The Microglial TREM2 Receptor Programs Hippocampal Development in a Mouse Model of Childhood Deprivation

Sahabuddin Ahmed, Christian Bowers, Jose Munoz-Martin, Sumit Jamwal, Basavaraju G. Sanganahalli, Kyle Chen, Lauryn Giuliano, Zoë A. MacDowell Kaswan, Fahmeed Hyder, X.William Yang, Arie Kaffman

The paper shows that TREM2 deficiency contributes to impaired microglial pruning and hippocampal dysfunction in a mouse model of childhood deprivation, and that TREM2 overexpression can rescue these deficits.

Brain Behavior and Immunity · Mar 24, 2026Peer-reviewedNeuroscience