The Microglial TREM2 Receptor Programs Hippocampal Development in a Mouse Model of Childhood Deprivation
Sahabuddin Ahmed, Christian Bowers, Jose Munoz-Martin…·Arie Kaffman
The paper shows that TREM2 deficiency contributes to impaired microglial pruning and hippocampal dysfunction in a mouse model of childhood deprivation, and that TREM2 overexpression can rescue these deficits.