Cell BiologybioRxivPreprint
Intrinsic self-organization of integrin nanoclusters within focal adhesions is required for cellular mechanotransduction
Kashish Jain, Kyna Yu En Lim, Michael P. Sheetz…·Rishita Changede
The paper shows that integrin nanoclusters self-organize within focal adhesions at an optimal distance to enable mechanotransduction, with cytoplasmic factors like talin and FHOD1 playing key roles.
DOI 10.1101/2023.11.20.567975