Author

L. A. Ju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. D. Cox· 2 shared A.-N. Cho· 1 shared C. A. Ng· 1 shared C. Zhu· 1 shared D. Cheng· 1 shared D. Fatkin· 1 shared F. Jiang· 1 shared F. Kong· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioengineering

C. D. Cox

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Force-regulated spontaneous conformational changes of integrins α5β1 and αVβ3

Y. Chen, F. Kong, Z. Li, L. A. Ju, C. Zhu

This study compares force-induced conformational changes in integrin ectodomains α5β1 and αVβ3, revealing distinct mechanical behaviors and energy landscapes.

bioRxiv · Jan 9, 2023 · PreprintBiophysics

3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay

Y. Zhang, F. Jiang, Y. C. Zhao, Y. Wang, S. S. S. Aye, A.-N. Cho, G. Fang, C. D. Cox, H. Zreiqat, Z. F. Lu, H. Lu, L. A. Ju

This paper introduces a 3D spheroid-microvasculature-on-a-chip model to study tumor-endothelium mechanobiology interactions under controlled flow conditions.

bioRxiv · Nov 19, 2022Bioengineering

Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations

J. V. Li, C. A. Ng, D. Cheng, M. Yao, Y. Guo, Z.-Y. Yu, Y. Ramaswamy, L. A. Ju, P. W. Kuchel, M. P. Feneley, D. Fatkin, C. D. Cox

The paper shows that N-linked glycosylation in Piezo1 channels is essential for plasma membrane trafficking and that mutations affecting this process are linked to disease.

bioRxiv · Nov 30, 2020Biophysics