Author

L. A. Mike

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

S. N. Smith· 3 shared H. L. T. Mobley· 2 shared M. A. Bachman· 2 shared A. J. Stark· 1 shared A. Sintsova· 1 shared B. Ring· 1 shared C. A. Sarkissan· 1 shared C. Alteri· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

S. N. Smith

Mutual co-authors in cluster

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4 papers

Recent·Most cited

The Klebsiella pneumoniae ter operon enhances stress tolerance

S. Mason, J. Vornhagen, S. N. Smith, L. A. Mike, H. A. Mobley, M. A. Bachman

This study identifies the ter operon in Klebsiella pneumoniae as a stress tolerance factor, enhancing fitness in the gut and bladder by protecting against environmental stressors.

bioRxiv · Dec 2, 2022 · PreprintMicrobiology

Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc

S. Khadka, B. Ring, L. R. Krzeminski, M. Hathaway, R. S. Walker, H. Mobley, L. A. Mike

This study identifies Wzc mutations as a mechanism for increased mucoidy in K. pneumoniae without altering EPS abundance, independent of rmp status.

bioRxiv · Jun 5, 2022Microbiology

A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness

L. A. Mike, A. J. Stark, V. Forsyth, J. Vornhagan, S. N. Smith, M. A. Bachman, H. L. T. Mobley

This study identifies genes affecting capsule and hypermucoviscosity in Klebsiella pneumoniae, showing their integration with central metabolism for bacterial fitness.

bioRxiv · Jun 22, 2020Microbiology

Optimization of an Experimental Vaccine to Prevent Escherichia coli Urinary Tract Infection

V. S. Forsyth, S. D. Himpsl, S. N. Smith, C. A. Sarkissan, L. A. Mike, J. A. Stocki, A. Sintsova, C. Alteri, H. L. T. Mobley

This study optimizes an intranasal vaccine against UPEC UTI using dmLT adjuvant and Hma/IutA antigens, significantly reducing bladder colonization.

mBio · Apr 28, 2020Peer-reviewedMicrobiology