Optical Control of G-Actin with a Photoswitchable Latrunculin
N. A. Veprek, M. H. Cooper, L. Laprell, E. J.-N. Yang, S. Folkerts, R. Bao, T. G. Oertner, L. A. Pon, J. B. Zuchero, D. H. Trauner
This paper introduces OptoLat, a photoswitchable latrunculin that controls G-actin dynamics optically, showing its effects on actin polymerization in various cell types and tissues.
bioRxiv · Jul 17, 2023Pharmacology & Toxicology