Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 Spike protein
C. C. Kuhn, N. Basnet, S. Bodakuntla, P. Alvarez- Brecht, S. Nichols, A. Martinez-Sanchez, L. Agostini, Y.-M. Soh, J. Takagi, C. Biertumpfel, N. Mizuno
This study observes SARS-CoV-2 Spike protein-induced platelet deformation and activation using cryo-ET and live imaging, identifying integrin vβ3 as a binding target.
bioRxiv · Nov 22, 2022Cell Biology