The antifungal activity of cymoxanil is associated with proton pump inhibition and disruption of plasma membrane potential
F. Mendes, H. Meyer, L. Amaral, B. Castro, M. Schuldiner, M. J. Sousa, S. Chaves
This study investigates the antifungal mechanism of cymoxanil, finding it disrupts plasma membrane potential and inhibits proton pumps in yeast, suggesting a mode of action involving membrane transport and acidification.
bioRxiv · Mar 1, 2024 · PreprintCell Biology