Cell competition, the kinetics of thymopoiesis and thymus cellularity are regulated by double negative 2 to 3 early thymocytes
C. V. Ramos, L. Ballesteros-Arias, J. G. Silva, R. A. Paiva, M. Nogueira, J. Carneiro, E. Gjini, V. C. Martins
The paper investigates how cell competition between DN2 and DN3e thymocytes regulates thymopoiesis and thymus cellularity through a feedback loop involving DN2b expansion and interleukin 7.
bioRxiv · Dec 21, 2019Immunology