Author

V. C. Martins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

R. A. Paiva· 3 shared C. V. Ramos· 2 shared A. G. Sousa· 1 shared E. Gjini· 1 shared J. Carneiro· 1 shared J. G. Silva· 1 shared J. Lilue· 1 shared L. Ballesteros-Arias· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

R. A. Paiva

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interleukin 7 receptor drives Early T lineage Progenitor expansion

R. A. Paiva, V. C. Martins

This study shows that IL-7/IL-7r signaling is essential for proliferation and survival of immature early T lineage progenitors (ETP) following thymus seeding.

bioRxiv · Oct 23, 2021 · PreprintImmunology

Self-renewal of double negative 3 (DN3) early thymocytes allows for thymus autonomy but compromises the β-selection checkpoint

R. A. Paiva, A. G. Sousa, C. V. Ramos, M. Avila, J. Lilue, T. Paixao, V. C. Martins

The paper shows DN3e thymocytes can self-renew and maintain thymopoiesis autonomously but bypass β-selection, risking leukemia.

bioRxiv · Jun 9, 2020 · PreprintImmunology

Cell competition, the kinetics of thymopoiesis and thymus cellularity are regulated by double negative 2 to 3 early thymocytes

C. V. Ramos, L. Ballesteros-Arias, J. G. Silva, R. A. Paiva, M. Nogueira, J. Carneiro, E. Gjini, V. C. Martins

The paper investigates how cell competition between DN2 and DN3e thymocytes regulates thymopoiesis and thymus cellularity through a feedback loop involving DN2b expansion and interleukin 7.

bioRxiv · Dec 21, 2019Immunology