Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation
S. Ualiyeva, E. R. Lemire, E. C. Aviles, A. Boyd, C. Wong, J. Lai, T. Liu, I. Matsumoto, N. A. Barrett, J. A. Boyce, A. L. Haber, L. Bankova
The paper shows that tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically drive lung type 2 inflammation in response to aeroallergens.
bioRxiv · Sep 26, 2021Immunology