Author

L. Barile

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Gori· 2 shared A. Radeghieri· 2 shared A. Zendrini· 2 shared G. Bergamaschi· 2 shared M. Cretich· 2 shared M. Romano· 2 shared R. Frigerio· 2 shared A. Alimonti· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

A. Gori

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel ionic model for matured and paced atrial-like hiPSC-CMs integrating IKur and IKCa currents

S. Botti, C. Bartolucci, C. Altomare, M. Paci, L. Barile, R. Krause, L. F. Pavarino, S. Severi

This paper develops an atrial-specific in-silico model of stem cell-derived cardiomyocytes integrating IKur and IKCa currents, validated against experimental data to improve drug testing and understanding of atrial fibrillation.

bioRxiv · Jan 12, 2024 · PreprintBioengineering

Addressing heterogeneity in direct analysis of Extracellular Vesicles and analogues using Membrane-Sensing Peptides as Pan-Affinity Probes

A. Gori, R. Frigerio, P. Gagni, J. Burrello, S. Panella, A. Raimondi, G. Bergamaschi, G. Lodigiani, M. Romano, A. Zendrini, A. Radeghieri, L. Barile, M. Cretich

This paper introduces Membrane-Sensing Peptides (MSP) as universal affinity ligands for analyzing Extracellular Vesicles and analogues, demonstrating their ability to detect EV-associated epitopes in clinical samples without prior isolation.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

Mitochondrial DNA released by senescent cells triggers immunosuppression in cancer

P. Lai, L. Liu, N. Bancaro, M. Troiani, B. Cali, J. Chen, P. K. Singh, R. A. Arzola, G. Attanasio, N. Pernigoni, E. Pasquini, S. Mosole, A. Rinaldi, J. Sgrignani, Y. Li, , A. Alimonti

This study shows that mtDNA released by senescent cells triggers immunosuppression via PMN-MDSCs, and inhibiting this pathway enhances therapy-induced senescence in cancer.

bioRxiv · Aug 6, 2023 · PreprintCell Biology

Compositional profiling of extracellular vesicles/lipoproteins mixtures by AFM nanomechanical imaging

A. Ridolfi, L. Conti, M. Brucale, R. Frigerio, J. Cardellini, A. Musico, M. Romano, A. Zendrini, L. Polito, G. Bergamaschi, A. Gori, C. Montis, L. Barile, D. Berti, A. Radeghieri, , F. Valle

This paper introduces an AFM-based method to distinguish and quantify lipoproteins and extracellular vesicles in mixed samples using nanomechanical imaging.

bioRxiv · Jul 19, 2022Biophysics