Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity
N. Pardo-Lorente, A. Gkanogiannis, L. Cozzuto, A. Ganez Zapater, L. Espinar, L. Garcia-Lopez, R. G. Aydin, E. Darai, J. Severino, L. Batlle-Morera, J. Ponomarenko, S. Sdelci
This study shows that nuclear MTHFD2 is essential for mitosis by maintaining centromere integrity and preventing chromosomal abnormalities in cancer cells.
bioRxiv · Jun 1, 2023 · PreprintCell Biology