SEC-seq: Association of molecular signatures with antibody secretion in thousands of single human plasma cells
R. Y.-H. Cheng, J. de Rutte, A. R. Ott, L. Bosler, W.-Y. Kuo, J. Liang, B. E. Hall, D. J. Rawlings, D. Di Carlo, R. G. James
The paper introduces SEC-seq, a method to link antibody secretion with surface markers and transcriptomes in single human plasma cells, revealing pathways associated with high IgG secretion.
bioRxiv · Aug 25, 2022Bioengineering