Author

L. Choppavarapu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:Hi-C· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

V. X. Jin· 2 shared G. Leone· 1 shared K. Fang· 1 shared M. Kahn· 1 shared T. Li· 1 shared T. Liu· 1 shared X. Hu· 1 shared Y. Zhou· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

V. X. Jin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity and tumor-specific looping-mediated biological pathways

L. Choppavarapu, K. Fang, T. Liu, V. X. Jin

The paper uses Hi-C profiling in breast tissues to reveal 3D chromatin-regulated tumor heterogeneity and identifies CA2 as a driver of tamoxifen resistance through enhancer-promoter looping.

bioRxiv · Mar 13, 2024 · PreprintCancer Biology

Reprogramming of 3D chromatin domains by antagonizing the β-catenin/CBP interaction attenuates insulin signaling in pancreatic cancer

Y. Zhou, T. Li, Z. He, L. Choppavarapu, X. Hu, G. Leone, M. Kahn, V. X. Jin

This study shows that inhibiting β-catenin/CBP interaction with ICG-001 alters 3D chromatin structure in pancreatic cancer, affecting insulin signaling and promoting tumor growth.

bioRxiv · Nov 10, 2023Cancer Biology