Author

V. X. Jin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Choppavarapu· 2 shared A. Mathison· 1 shared A. Salmonson· 1 shared A. Thomas· 1 shared G. A. Lomberk· 1 shared G. Leone· 1 shared G. Pollin· 1 shared G. Urrutia· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

L. Choppavarapu

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3 papers

Recent·Most cited

EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas

G. Pollin, A. Mathison, T. Milech de Assuncao, A. Thomas, L. Zeighami, A. Salmonson, H. Liu, G. Urrutia, P. Vankayala, S. J. Pandol, M. T. Zimmermann, J. L. Iovanna, V. X. Jin, R. A. Urrutia, G. A. Lomberk

bioRxiv · Mar 14, 2024Cancer Biology

Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity and tumor-specific looping-mediated biological pathways

L. Choppavarapu, K. Fang, T. Liu, V. X. Jin

The paper uses Hi-C profiling in breast tissues to reveal 3D chromatin-regulated tumor heterogeneity and identifies CA2 as a driver of tamoxifen resistance through enhancer-promoter looping.

bioRxiv · Mar 13, 2024 · PreprintCancer Biology

Reprogramming of 3D chromatin domains by antagonizing the β-catenin/CBP interaction attenuates insulin signaling in pancreatic cancer

Y. Zhou, T. Li, Z. He, L. Choppavarapu, X. Hu, G. Leone, M. Kahn, V. X. Jin

This study shows that inhibiting β-catenin/CBP interaction with ICG-001 alters 3D chromatin structure in pancreatic cancer, affecting insulin signaling and promoting tumor growth.

bioRxiv · Nov 10, 2023Cancer Biology