IL-22 induced cell extrusion and IL-18-induced pyroptosis prevent and cure rotavirus infection
Z. A. Zhang, J. Zou, Z. Shi, B. Zhang, L. Etienne-Mesmin, B. Chassaing, A. Gewirtz
This study shows that IL-22 and IL-18 prevent and cure rotavirus infection by distinct mechanisms involving cell extrusion and pyroptosis in intestinal epithelial cells.
bioRxiv · Sep 18, 2019 · PreprintImmunology