B. Chassaing

Maternal diet alters offspring early life host-microbiota communication through goblet cells, resulting in long-lasting diseases susceptibility

This study shows maternal diet affects offspring microbiota and health through goblet cells, leading to long-term disease susceptibility.

Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies

This study shows that CDT toxin from Clostridioides difficile induces biofilm-like microcolonies, increasing colonization and persistence in intestinal models and infected mice.

Regulation of Lung Immune Tone by the Gut-Lung Axis via Dietary Fiber, Gut Microbiota, and Short-Chain Fatty Acids

This study shows that dietary fiber and gut microbiota influence lung immune tone via short-chain fatty acids, reducing inflammation and lung injury in mice.

Obesity promotes Fumonisin B1 toxicity and induces hepatitis

This study shows that obesity increases susceptibility to fumonisin B1 toxicity, leading to gut dysbiosis and severe liver inflammation.

Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota that Protects from Metabolic Diseases

This study shows that tolerogenic dendritic cells promote a gut microbiota that prevents metabolic diseases by enhancing butyrate production and reducing inflammation.

IL-22 induced cell extrusion and IL-18-induced pyroptosis prevent and cure rotavirus infection

This study shows that IL-22 and IL-18 prevent and cure rotavirus infection by distinct mechanisms involving cell extrusion and pyroptosis in intestinal epithelial cells.

Innate immune recognition of a bacterial MAMP leads to conditional activation of pro- or anti-inflammatory responses

This study shows that flagellin, a bacterial MAMP, can trigger either pro- or anti-inflammatory responses depending on the tissue's physiological state and context.

Specific targeting of intestinal Prevotella copri by a Listeria monocytogenes bacteriocin

This study identifies a Listeria bacteriocin that specifically targets Prevotella copri, showing microbiota-dependent effects on Listeria infection in mice.

Gut microbiota influence B cell function in a TLR5-dependent manner

This study shows TLR5 signaling in epithelial cells affects B cell populations and antibody responses, leading to microbiome dysbiosis in TLR5-deficient mice.