Author

A. Gewirtz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Chassaing· 2 shared A. Kolykhalov· 1 shared A. L. Greninger· 1 shared B. Zhang· 1 shared C. M. Lieber· 1 shared E. B. Sobolik· 1 shared F. Dejardin· 1 shared F. Langa Vives· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

B. Chassaing

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets

R. K. Plemper, R. Cox, J. D. Wolf, N. A. P. Lieberman, C. M. Lieber, H.-J. Kang, Z. M. Sticher, J.-J. Yoon, M. K. Andrews, M. Govindarajan, R. E. Krueger, E. B. Sobolik, M. G. Natchus, A. Gewirtz, R. deSwart, , A. L. Greninger

This study shows that prior respiratory virus infections worsen measles severity in ferrets and that antiviral treatment can mitigate immune amnesia and disease outcomes regardless of treatment timing.

bioRxiv · Sep 1, 2023Microbiology

IL-22 induced cell extrusion and IL-18-induced pyroptosis prevent and cure rotavirus infection

Z. A. Zhang, J. Zou, Z. Shi, B. Zhang, L. Etienne-Mesmin, B. Chassaing, A. Gewirtz

This study shows that IL-22 and IL-18 prevent and cure rotavirus infection by distinct mechanisms involving cell extrusion and pyroptosis in intestinal epithelial cells.

bioRxiv · Sep 18, 2019 · PreprintImmunology

Innate immune recognition of a bacterial MAMP leads to conditional activation of pro- or anti-inflammatory responses

J. H. Park, S. Cornick, G. Nigro, G. Bertin, F. Dejardin, R. Smits, M. Berard, F. Langa Vives, I. Gomperts Boneca, A. Gewirtz, B. Chassaing, N. Barnich, P. Sansonetti, G. Eberl

This study shows that flagellin, a bacterial MAMP, can trigger either pro- or anti-inflammatory responses depending on the tissue's physiological state and context.

bioRxiv · Jul 28, 2019 · PreprintImmunology