Author

L. F. Gumy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:metagenomics· 1

Frequent Co-Authors

L. M. Malone· 2 shared P. C. Fineran· 2 shared S. A. Jackson· 2 shared C. Garcia-Doval· 1 shared C. Warnecke· 1 shared D. Mayo-Munoz· 1 shared H. G. Hampton· 1 shared K. R. Harding· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

L. M. Malone

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Author profile →

2 papers

Recent·Most cited

Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection

D. Mayo-Munoz, L. M. Smith, C. Garcia-Doval, L. M. Malone, K. R. Harding, S. A. Jackson, H. G. Hampton, R. D. Fagerlund, L. F. Gumy, P. C. Fineran

The paper shows type III CRISPR-Cas systems provide immunity against jumbo phages by degrading bacterial DNA and disrupting phage replication through an accessory nuclease, leading to abortive infection.

bioRxiv · Jun 20, 2022Microbiology

A nucleus-forming jumbophage evades CRISPR-Cas DNA targeting but is vulnerable to type III RNA-based immunity

L. M. Malone, S. L. Warring, S. A. Jackson, C. Warnecke, P. P. Gardner, L. F. Gumy, P. C. Fineran

The paper identifies a jumbophage that evades DNA-targeting CRISPR-Cas systems but is vulnerable to type III RNA-based immunity, revealing the role of nucleus-like structures in immune evasion.

bioRxiv · Sep 25, 2019Microbiology