Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads
I. B. L. Ramiro, W. E. Bjoern-Yoshimoto, J. S. Imperial, J. Gajewiak, M. Watkins, D. Taylor, W. Resager, B. Ueberheide, H. Brauner-Osborne, F. G. Whitby, C. P. Hill, L. F. Martin, A. Patwardhan, G. P. Concepcion, B. M. Olivera, H. Safavi-Hemami
The paper identifies somatostatin venom analogs from fish-hunting cone snails, showing their potential as therapeutic leads for pain, cancer, and endocrine disorders.
bioRxiv · Oct 26, 2021Biochemistry