Author

L. F. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

S. J. Altschuler· 3 shared A. B. Chase· 1 shared A. Bogdanov· 1 shared A. J. O'Donoghue· 1 shared B. Hann· 1 shared C. Y. Zhang· 1 shared E. Barbosa Da Silva· 1 shared H. Hammerlindl· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

S. J. Altschuler

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Author profile →

4 papers

Recent·Most cited

Small Molecule in situ Resin Capture - A Compound First Approach to Natural Product Discovery.

A. Bogdanov, M. N. Salib, A. B. Chase, H. Hammerlindl, M. N. Muskat, S. Luedtke, E. Barbosa Da Silva, A. J. O'Donoghue, L. F. Wu, S. J. Altschuler, T. F. Molinski, P. R. Jensen

This paper introduces a compound-first approach to natural product discovery called SMIRC, which captures structurally complex small molecules directly from environments, leading to the discovery of new compounds and classes.

bioRxiv · Mar 2, 2023 · PreprintBiochemistry

Transit-amplifying cells coordinate changes in intestinal epithelial cell-type composition

L. E. Sanman, I. W. Chen, J. M. Bieber, V. Steri, B. Hann, L. F. Wu, S. J. Altschuler

The paper identifies that modulating transit-amplifying cell proliferation alters intestinal epithelial cell-type composition through lineage-based mechanisms.

bioRxiv · Mar 12, 2020Cell Biology

Inhibitory effect of Bacillus subtilis WL-2 and its IturinA lipopeptides against Phytophthora infestans

Y. Y. Wang, C. Y. Zhang, L. F. Wu, L. Wang, W. B. Gao, J. Z. Jiang, Y. Q. Wu

This paper identifies Bacillus subtilis WL-2 and its IturinA lipopeptides as effective inhibitors of Phytophthora infestans mycelium growth through mechanisms involving cell membrane damage, oxidative stress, and mitochondrial dysfunction.

bioRxiv · Aug 29, 2019 · PreprintMicrobiology

Response-Time Behaviors Of Intercellular Communication Network Motifs

K. Thurley, L. F. Wu, S. J. Altschuler

The paper models cell-to-cell communication networks using response-time distributions to explain cytokine secretion onset times in T cells and predict network structure from input-output measurements.

bioRxiv · Aug 23, 2017Biophysics