Author

L. Fairchild

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Chow· 1 shared A. Rizzi· 1 shared A. Schurer· 1 shared C. Adura· 1 shared C. B. Gustafson· 1 shared C. D. Campbell· 1 shared C. Famulare· 1 shared C. S. Leslie· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Chow

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2 papers

Recent·Most cited

Clonal hematopoiesis detection in cancer patients using cell free DNA sequencing

L. Fairchild, J. Whalen, K. D'Aco, J. Wu, C. B. Gustafson, N. Solovieff, F. Su, R. Leary, C. D. Campbell, O. A. Balbin

The paper trains a machine learning model to detect clonal hematopoiesis in cancer patients using cell-free DNA sequencing and characterizes associated tumor microenvironment changes.

bioRxiv · Oct 27, 2021Cancer Biology

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

G. Minuesa, S. K. Albanese, A. Chow, A. Schurer, S.-M. Park, C. Z. Rotsides, J. Taggart, A. Rizzi, L. N. Naden, T. Chou, S. Gourkanti, D. Cappel, M. C. Passarelli, L. Fairchild, C. Adura, , M. G. Kharas

This study identifies Ro 08-2750 as a small molecule that targets MSI2 RNA-binding activity, inducing differentiation, apoptosis, and reduced disease burden in AML models.

Nature Communications · Jun 19, 2019Peer-reviewedCancer Biology