Author

M. C. Passarelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Chow· 1 shared A. Rizzi· 1 shared A. Schurer· 1 shared C. Adura· 1 shared C. Famulare· 1 shared C. S. Leslie· 1 shared C. Z. Rotsides· 1 shared D. Cappel· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Chow

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Author profile →

2 papers

Recent·Most cited

Two Isoleucyl tRNAs that Decode 'Synonymous' Codons Divergently Regulate Breast Cancer Progression

L. B. Earnest-Noble, D. Hsu, H. Asgharian, N. Mandayam, M. C. Passarelli, H. Goodarzi, S. F. Tavazoie

The paper shows that two isoleucyl tRNAs decode synonymous codons and have opposing effects on breast cancer progression by regulating translation of growth-promoting genes.

bioRxiv · Apr 22, 2021 · PreprintCancer Biology

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

G. Minuesa, S. K. Albanese, A. Chow, A. Schurer, S.-M. Park, C. Z. Rotsides, J. Taggart, A. Rizzi, L. N. Naden, T. Chou, S. Gourkanti, D. Cappel, M. C. Passarelli, L. Fairchild, C. Adura, , M. G. Kharas

This study identifies Ro 08-2750 as a small molecule that targets MSI2 RNA-binding activity, inducing differentiation, apoptosis, and reduced disease burden in AML models.

Nature Communications · Jun 19, 2019Peer-reviewedCancer Biology