Disordered regions of human eIF4B orchestrate a dynamic self-association landscape
B. C. Swain, P. Sarkis, V. Ung, S. Rousseau, L. Fernandez, A. Meltonyan, V. E. Aho, D. Mercadante, C. D. Mackereth, M. Aznauryan
This study investigates the dynamic self-association of eIF4B's intrinsically disordered region using experiments and simulations, revealing its role in forming oligomers and phase separation.
bioRxiv · Jun 21, 2024Biophysics