L. Finzi

Force and the α-C-terminal domains bias RNApolymerase recycling

The paper investigates how force and α-C-terminal domains influence RNA polymerase recycling after termination, showing force biases diffusion direction and promoter recognition.

Reciprocating RNA Polymerase batters throughroadblocks

This study investigates how RNA polymerase navigates protein roadblocks in E. coli, showing force-dependent effects and the role of GreA in facilitating passage.

Transcription disrupts DNA-scaffolded bacteriophage repressor complexes

The paper shows that DNA-scaffolded bacteriophage repressor complexes do not effectively block transcription by E. coli RNA polymerase.

A thermodynamic model of bacterial transcription

This paper introduces a thermodynamic model of bacterial transcriptional pausing that predicts pause kinetics and factors like tension and GreA.

Ionic strength modulates HU protein-induced DNA supercoiling

This study investigates how ionic strength affects HU protein-induced DNA supercoiling and compaction using single-molecule techniques.

Positive supercoiling favors transcription elongation through lac repressor-mediated DNA loops

The paper shows that positive supercoiling helps RNA polymerase bypass LacI-mediated DNA loops in E. coli by reducing pauses and enhancing dissociation of roadblocks.

Negative DNA supercoiling makes protein-mediated looping deterministic and ergodic within the bacterial doubling time

The paper shows that negative DNA supercoiling reduces stochasticity in protein-mediated DNA looping, making it deterministic and ergodic within bacterial doubling time.

Nanomechanics of negatively supercoiled diaminopurine-substituted DNA

This study investigates how diaminopurine substitution affects DNA conformational dynamics under tension and unwinding, revealing distinct mechanical properties of DAP-substituted DNA.