Author

L. G. Dent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. Bakal· 3 shared J. E. Sero· 2 shared C. Dunsby· 1 shared F. Butera· 1 shared H. Sparks· 1 shared I. Jones· 1 shared I. Munro· 1 shared J. S. Chaudhary· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCell Biology

C. Bakal

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Author profile →

3 papers

Recent·Most cited

Coupling of Nuclear Translocation to Cell Size Promotes Robustness to Fluctuations in YAP/TAZ Concentration

I. Jones, M. A. Garcia, P. P. Vargas, M. Beykou, L. G. Dent, T. Choudhary, T. I. Roumeliotis, J. S. Chaudhary, J. E. Sero, C. Bakal

The paper shows that nuclear YAP/TAZ concentration remains stable during cell cycle despite whole-cell dilution, due to coupling with cell size and nuclear transport processes.

bioRxiv · Feb 6, 2023Cell Biology

Actin networks modulate heterogenous NF-κB dynamics in response to TNFα

F. Butera, J. E. Sero, L. G. Dent, C. Bakal

The paper investigates how actin networks influence NF-κB dynamics in PDAC cells, identifying feedback loops involving RELA, NUAK2, ARHGAP31, and RELB.

bioRxiv · Jan 19, 2022Cancer Biology

Environmentally dependent and independent control of cell shape determination by Rho GTPase regulators in melanoma

L. G. Dent, N. Curry, H. Sparks, V. Bousgouni, V. Maioli, S. Kumar, I. Munro, C. Dunsby, C. Bakal

This study compares cell shape determination in 2D and 3D environments using melanoma cells and identifies Rho GTPase regulators that modulate shape changes in response to environmental cues.

bioRxiv · Oct 11, 2021 · PreprintCell Biology