Author

F. Butera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Bakal· 3 shared A. Legrand· 1 shared A. Melcher· 1 shared A. Rullan· 1 shared C. Chan· 1 shared C. J. Lord· 1 shared D. B. Krastev· 1 shared E. Appleton· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Bakal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PARP inhibitors enhance reovirus-mediated cell killing through the death-inducing signaling complex (DISC) with an associated NF-kappa B-regulated immune response.

J. Kyula-Currie, V. Roulstone, J. Wright, F. Butera, A. Legrand, R. Elliott, M. McLaughlin, G. Bozhanova, D. B. Krastev, S. Pettitt, T. Tenev, M. T. B. Dillon, S. Foo, E. C. Patin, V. Jennings, , K. J. Harrington

This paper identifies PARP inhibitors as sensitizers for oncolytic reovirus by enhancing DISC-mediated apoptosis and NF-kappa B-driven immune responses.

bioRxiv · Dec 21, 2023 · PreprintCancer Biology

Re-engineering of TNFα-NF-κB signalling dynamics in cancer cells using pathogenic E. coli effectors

Q. Zhong, F. Butera, G. Frankel, C. Bakal

This study uses bacterial effectors to manipulate NF-κB signalling in cancer cells, showing that combining Tir, NleE, and TNF can eliminate 95% of pancreatic cancer cells with minimal NF-κB activation.

bioRxiv · Mar 3, 2023 · PreprintCell Biology

Actin networks modulate heterogenous NF-κB dynamics in response to TNFα

F. Butera, J. E. Sero, L. G. Dent, C. Bakal

The paper investigates how actin networks influence NF-κB dynamics in PDAC cells, identifying feedback loops involving RELA, NUAK2, ARHGAP31, and RELB.

bioRxiv · Jan 19, 2022Cancer Biology