Author

H. Sparks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 4 Approach:experimental assay· 3 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:imputation· 1

Frequent Co-Authors

C. Dunsby· 4 shared C. Bakal· 2 shared A. Behrens· 1 shared B. Akiyama· 1 shared B. Monogue· 1 shared C. Paterson· 1 shared G. Salbreux· 1 shared I. Munro· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersCell Biology

C. Dunsby

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture

L. Dvinskikh, H. Sparks, L. Brito, K. T. MacLeod, S. E. Harding, C. Dunsby

This study uses remote-refocusing light-sheet microscopy to image electromechanical coupling in co-cultured adult and hiPSC-derived cardiomyocytes, showing improved coupling over time.

bioRxiv · Jan 28, 2023Cell Biology

Environmentally dependent and independent control of cell shape determination by Rho GTPase regulators in melanoma

L. G. Dent, N. Curry, H. Sparks, V. Bousgouni, V. Maioli, S. Kumar, I. Munro, C. Dunsby, C. Bakal

This study compares cell shape determination in 2D and 3D environments using melanoma cells and identifies Rho GTPase regulators that modulate shape changes in response to environmental cues.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

Video-rate remote refocusing through continuous oscillation of a membrane deformable mirror.

T. Wright, H. Sparks, C. Paterson, C. Dunsby

This paper demonstrates a deformable mirror system for rapid refocusing in microscopy, achieving video-rate volumetric imaging with high Strehl metrics.

bioRxiv · Apr 27, 2021Bioengineering

Dual-view oblique plane microscopy (dOPM)

H. Sparks, L. Dent, C. Bakal, A. Behrens, G. Salbreux, C. Dunsby

This paper introduces a new dual-view oblique plane microscopy technique that improves resolution and reduces shadow artefacts in multi-cellular spheroid imaging.

bioRxiv · Sep 24, 2020Bioengineering

Disruption of Zika virus xrRNA1-dependent sfRNA1 production results in tissue-specific attenuated viral replication

H. Sparks, B. Monogue, B. Akiyama, J. Kieft, J. D. Beckham

This study shows that disrupting sfRNA1 production in ZIKV reduces viral replication in brain and placenta but not spleen, while still inducing neutralizing antibodies.

bioRxiv · Sep 10, 2020Microbiology