Structural basis of membrane targeting and coatomer assembly by human GBP1
T. I. Kuhm, L. Gross, C. de Agrela Pinto, S. T. Huber, C. Taisne, E. A. Giannopoulou, E. Pardon, J. Steyaert, S. J. Tans, A. J. Jakobi
This study determines the cryo-EM structure of human GBP1 dimer and coatomer assemblies, revealing how nucleotide binding and hydrolysis drive membrane targeting and coatomer formation.
bioRxiv · Mar 28, 2023Biophysics