Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis
R. Ungricht, L. Guibbal, M.-C. Lasbennes, V. Orsini, M. Beibel, A. Waldt, R. Cuttat, W. Carbone, A. Basler, G. Roma, F. Nigsch, J. Tchorz, D. Hoepfner, P. S. Hoppe
This study uses genome-wide CRISPR screening in human kidney organoids to identify novel regulatory mechanisms in nephrogenesis, including a new role for Jagged1 in controlling epithelial proliferation.
bioRxiv · May 26, 2021Cell Biology