Author

O. Goureau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:differential expression· 2 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

A. Ramani· 2 shared D. Dalkara· 2 shared E. Gabriel· 2 shared J. Gopalakrishnan· 2 shared S. Picaud· 2 shared A. Chaffiol· 1 shared A. Dentel· 1 shared A. Dilthey· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. Ramani

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion, and drug screening

A. Ramani, G. Pasquini, N. Gerkau, O. S. Vinchure, E. Gabriel, I. Rothenaigner, S. Lin, N. Altinisk, D. Rathinam, A. Mirsaidi, O. Goureau, L. Ricci-Vitiani, G. Q. d'alessandris, R. Pallini, B. Wollnik, , J. Gopalakrishnan

This study develops a high-throughput method to generate reliable human brain organoids for modeling microcephaly, glioma invasion, and drug screening.

bioRxiv · Oct 29, 2023Cell Biology

Inducible non-human primate models of retinal degeneration for testing end stage therapies and understanding disease mechanisms

D. Ail, D. Nava, I. P. Hwang, E. Brazhnikova, C. N. Jaillard, A. Dentel, C. Joffrois, L. Rousseau, J. Degardin, S. Bertin, J. A. Sahel, O. Goureau, S. Picaud, D. Dalkara

This study develops three inducible non-human primate models of retinal degeneration to test end-stage therapies and understand disease mechanisms.

bioRxiv · Dec 3, 2022 · PreprintBioengineering

SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects

J. Gopalakrishnan, A. Ramani, L. Mueller, P. Niklas Ostermann, E. Gabriel, A. Islam Pranty, A. Mueller-Shiffmann, A. Mariappan, O. Goureau, H. Gruell, A. Walker, M. Andree, S. Hauka, K. Wohlgemuth, H. Omran, , A. Dilthey

This study shows SARS-CoV-2 infects cortical neurons in 3D human brain organoids, causing neurodegeneration-like effects such as Tau mislocalization and neuronal death.

bioRxiv · May 20, 2020Cell Biology

Restoration of visual function by transplantation of optogenetically engineered photoreceptors

M. Garita-Hernandez, M. Lampic, A. Chaffiol, L. Guibbal, F. Routet, T. Santos-Ferreira, G. Gagliardi, S. Reichman, S. Picaud, J.-A. Sahel, O. Goureau, M. Ader, D. Dalkara, J. Duebel

This study shows that transplanting optogenetically engineered photoreceptors can restore visual function in blind mice through light-responsive responses at multiple retinal levels.

bioRxiv · Aug 29, 2018Bioengineering