Author

L. Hegazy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. Elgendy· 2 shared A. Chatterjee· 1 shared A. Hamilton· 1 shared A.-C. Valfort· 1 shared C. Billon· 1 shared J. Chrivia· 1 shared J. Huss· 1 shared J. K. Walker· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. Elgendy

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A Synthetic ERRα Agonist Induces an Acute AerobicExercise Response and Enhances Exercise Capacity

C. Billon, S. Banerjee, S. Situala, R. Welch, L. Hegazy, B. Elgendy, T. G. Oh, M. Kazantzis, A. Chatterjee, J. Chrivia, M. Hayes, W. Xu, A. Hamilton, J. Huss, L. Zhang, , T. Burris

A synthetic ERRα agonist activates an acute aerobic exercise genetic program in skeletal muscle, enhancing exercise capacity and mitochondrial function in mice.

bioRxiv · Oct 5, 2022 · PreprintPharmacology & Toxicology

Distinct REV-ERBα Conformational State Predicted by GaMD Simulations Leads to the Structure-Based Discovery of Novel REV-ERBα Antagonist

L. HEGAZY, A.-C. Valfort, T. P. Burris, B. Elgendy

This study uses GaMD simulations to identify a novel conformational state of REV-ERBα, enabling structure-based discovery of new antagonists.

bioRxiv · May 26, 2021 · PreprintBiophysics