The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH-oxidase activity
J. Martensson, M. Sundqvist, A. Manandhar, L. Ieremias, L. Linjie, T. Ulven, X. Xie, L. Bjorkman, H. Forsman
This study shows that FPR1 and FPR2 differentially regulate GPR84-mediated neutrophil NADPH-oxidase activity, with FPR2 reactivation amplifying ROS production and FPR1 suppressing it.
bioRxiv · Nov 13, 2020Immunology