Author

L. J. Conrad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

P. Proks· 2 shared S. J. Tucker· 2 shared E. P. Carpenter· 1 shared K. E. Rodstrom· 1 shared K. Rathje· 1 shared M. Schewe· 1 shared S. Rao· 1 shared T. Baukrowitz· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

P. Proks

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2 papers

Recent·Most cited

Effects of Ionic Strength on Gating and Permeation of TREK-2 K2P channels

L. J. Conrad, P. Proks, S. J. Tucker

This study investigates how ionic strength affects TREK-2 channel gating and permeation, finding that high internal K+ inhibits the channel through increased ionic strength, while BL1249 increases conductance but not open probability.

bioRxiv · Jul 8, 2021Biophysics

Multiple Mechanisms Underlie State-Independent Inhibitory Effects of Norfluoxetine on TREK-2 K2P Channels

P. Proks, M. Schewe, L. J. Conrad, S. Rao, K. Rathje, K. E. Rodstrom, E. P. Carpenter, T. Baukrowitz, S. J. Tucker

This study identifies multiple mechanisms by which norfluoxetine inhibits TREK-2 K2P channels, showing state-independent effects and interactions with filter stability and voltage-dependent gating.

bioRxiv · Oct 29, 2020Biophysics