Targeting Aryl Hydrocarbon Receptor with small molecule, 1'H-indole-3'-carbonyl -thiazole-4-carboxylic acid methyl ester blocked human glioma cell invasion via MYH9
l. j. Zhao, Q. t. Shu, H. Sun, Y. l. Ma, D. d. Kang, Y. t. Zhao, J. Lu, P. Gong, F. Yang, f. Wan
The paper shows that ITE, an AHR ligand, inhibits glioma cell migration and invasion by reducing MYH9 expression, which is critical for cell motility.
bioRxiv · Jan 13, 2020Cell Biology